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Scientific Overview Research Interest Summary Principal Investigators Emeritus Faculty Recent Publications
 
Research Interest Summary
 



Yuri Bushkin, Ph.D.
Theresa Chang, Ph.D.
Neeraj Chauhan, Ph.D.
Liang Chen, Ph.D.
Véronique Dartois, Ph.D.
Karl Drlica, Ph.D.
David Dubnau, Ph.D.
Eliseo A. Eugenin, Ph.D.
Marila Gennaro, M.D.
Jeanette Hahn, Ph.D.
Gilla Kaplan, Ph.D.
Fred Russell Kramer, Ph.D.
Barry Kreiswirth, Ph.D.
Min Lu, Ph.D.
Salvatore A.E. Marras, Ph.D.
Leonard Mindich, Ph.D.
Arkady Mustaev, Ph.D.
Jyothi F Nagajyothi, Ph.D.
David Perlin, Ph.D.
Richard Pine, Ph.D.
Abraham Pinter, Ph.D.
Marcela G Rodriguez, Ph.D.
Lanbo Shi, Ph.D.
Selvakumar Subbian, Ph.D.
Sanjay Tyagi, Ph.D.
Christopher Vinnard, M.D., M.P.H., M.S.C.E.
Chaoyang Xue,Ph.D.
Yanan Zhao, Ph.D.
Xilin Zhao, Ph.D.




Yuri Bushkin, Ph.D.

Studies antigen presentation in two model systems: during organ transplantation and in the course of mycobacterial infection.




Theresa Chang, Ph.D.

Studies the role of innate immunity in sexually transmitted infection-mediated enhancement of HIV infection, and HIV infection of human peritoneal macrophages.




Neeraj Chauhan, Ph.D.

Studies the opportunistic human pathogenic yeast, Candida albicans.




Liang Chen, Ph.D.

Studies the molecular epidemiology of antimicrobial resistance and infectious disease, with particular focus on carbapenem-resistant Enterobacteriaceae (CRE) and Methicillin-resistant Staphylococcus aureus (MRSA).




Véronique Dartois, Ph.D.

Studies the the pharmacokinetics and pharmacodynamics of anti-tuberculosis agents.




Karl Drlica, Ph.D.

Studies bacterial chromosome structure to understand how disease causing organisms become drug resistant.




David Dubnau, Ph.D.

Studies mechanisms bacterial cells use to share genetic information, and the consequences of such sharing for evolution, survival and drug resistance.




Eliseo A. Eugenin, Ph.D.

Studies the role of cellular communication systems in the pathogenesis of CNS viruses




Jeanette Hahn, Ph.D.

Studies the requirements for polar localization and delocalization of specific proteins involved in the competent state of Bacillus subtilis.




Marila Gennaro, M.D.

Studies immune responses to proteins secreted by Mycobacterium tuberculosis and evaluates their use for diagnostic purposes. She also studies the effects of host immunity on transcription and antigen composition of M. tuberculosis during infection, and the implications for immunodiagnostics and vaccine design.




Gilla Kaplan, Ph.D.

Studies diverse ways in which patients' immune systems respond to infection by TB and HIV. She carries out major clinical research programs in South Africa and other countries.




Fred Russell Kramer, Ph.D.

Studies RNA biology and designs novel nucleic acid molecules for diagnostic and therapeutic application. He is the co-inventor of molecular beacons.




Barry Kreiswirth, Ph.D.

Studies the molecular epidemiology of infectious agents including Mycobacterium tuberculosis and methicillin resistant S. aureus, using state-of-the-art DNA typing methods. He is the Director of the PHRI TB Center.




Min Lu, Ph.D.

Studies the molecular mechanisms that underlie HIV-1 entry into target cells.




Salvatore A.E. Marras, Ph.D.

Studies the properties of fluorescent nucleic acid hybridization probes and develops novel probe chemistries.





Leonard Mindich, Ph.D.

Studies the mechanisms by which virus structures are assembled, the strategies involved in the packaging and replication of their genomes.





Arkady Mustaev, Ph.D.

Studies the development of chemical and physico-chemical approaches for studies of proteins, nucleic acids and their complexes.





Jyothi F Nagajyothi, Ph.D.

Studies the role of lipids in the pathogenesis of chagasic cardiomyopathy.




David Perlin, Ph.D.

Studies the nature of clinical antifungal drug resistance, rapid detection of pathogenic microorganisms, and application of small animal infection models.




Richard Pine, Ph.D.

Studies the regulation of gene expression that determines cellular response to infection by M. tuberculosis and/or HIV-1, focusing on the involvement of cytokine systems and other aspects of interactions among cells.




Abraham Pinter, Ph.D.

Studies the envelope proteins of HIV and other retroviruses, with a major emphasis on relating structure to function and immunological properties.




Marcela G Rodriguez, Ph.D.

Studies the adaptive and regulatory response that allows Mycobacterium tuberculosis to survive iron deficiency in the host.




Lanbo Shi, Ph.D.

Studies the mechanisms of metabolic and physiological adaptation of Mycobacterium tuberculosis during infection.




Selvakumar Subbian, Ph.D.

Studies host-pathogen interactions in tuberculosis. His research is also focused on exploring host-directed therapeutic approaches to improve tuberculosis treatment as well as deciphering the molecular correlates of host immune responses in infectious diseases.




Sanjay Tyagi, Ph.D.

Studies the behavior of nucleic acids in living cells. He is the co-inventor of molecular beacons.




Christopher Vinnard, M.D., M.P.H., M.S.C.E.

Studies patient factors that drive variability in the pharmacokinetics of anti-infective agents, with a focus on tuberculosis.




Chaoyang Xue, Ph.D.

Studies host-pathogen interactions in Cryptococcus.




Yanan Zhao, Ph.D.

Studies rapid molecular diagnostics for fungal/bacterial infections and antifungal drug resistance, and drug efficacy evaluation using animal models.




Xilin Zhao, Ph.D.

Studies bacterial stress response networks and their roles in antimicrobial tolerance, persistence, and resistance. Develops novel platforms for affordable molecular diagnosis of diseases. Explores unconventional approaches for rapid cure of tuberculosis.

 
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