Yuri Bushkin, Ph.D.
Loren Day, Ph.D.
Karl Drlica, Ph.D.
David Dubnau, Ph.D.
Marila Gennaro, M.D.
Gilla Kaplan, Ph.D.
Fred Kramer, Ph.D.
Barry Kreiswirth, Ph.D.
Leonard Mindich, Ph.D.
Harvey Penefsky, Ph.D.
David Perlin, Ph.D.
Richard Pine, Ph.D.
Abraham Pinter, Ph.D.
Issar Smith, Ph.D.
Patricia Soteropoulos, Ph.D.
Sanjay Tyagi, Ph.D.
David Wah, Ph.D.
Shuishu Wang, Ph.D.




Yuri Bushkin, Ph.D.

Studies antigen presentation in two model systems: during organ transplantation and in the course of mycobacterial infection.




Loren Day, Ph.D.

Studies the structures of a variety of filamentous bacterial viruses in order to understand structural principles and evolutionary relationships.




Karl Drlica, Ph.D.

Studies bacterial chromosome structure to understand how disease causing organisms become drug resistant.




David Dubnau, Ph.D.

Studies mechanisms bacterial cells use to share genetic information, and the consequences of such sharing for evolution, survival and drug resistance.




Marila Gennaro, M.D.

Studies immune responses to proteins secreted by Mycobacterium tuberculosis and evaluates their use for diagnostic purposes. She also studies the effects of host immunity on transcription and antigen composition of M. tuberculosis during infection, and the implications for immunodiagnostics and vaccine design.




Gilla Kaplan, Ph.D.

Studies diverse ways in which patients' immune systems respond to infection by TB and HIV. She carries out major clinical research programs in South Africa and other countries.




Fred Kramer, Ph.D.

Studies RNA biology and designs novel nucleic acid molecules for diagnostic and therapeutic application. He is the co-inventor of molecular beacons.




Barry Kreiswirth, Ph.D.

Studies the molecular epidemiology of infectious agents including Mycobacterium tuberculosis and methicillin resistant S. aureus, using state-of-the-art DNA typing methods. He is the Director of the PHRI TB Center.




Leonard Mindich, Ph.D.

Studies the mechanisms by which virus structures are assembled the strategies involved in the packaging and replication of their genomes.




Harvey Penefsky, Ph.D.

Studies the molecular mechanism of energy production by cells.




David Perlin, Ph.D.

Studies the nature of clinical antifungal drug resistance, the processes involved in the transport of molecules in and out of cells, and rapid detection of pathogenic microorganisms.




Richard Pine, Ph.D.

Studies the regulation of gene expression that determines cellular response to infection by M. tuberculosis and/or HIV-1, focusing on the involvement of cytokine systems and other aspects of interactions among cells.




Abraham Pinter, Ph.D.

Studies the envelope proteins of HIV and other retroviruses, with a major emphasis on relating structure to function and immunological properties.




Issar Smith, Ph.D.

Studies virulence factors of the bacterium Mycobacterium tuberculosis that enable it to cause TB.




Patricia Soteropoulos, Ph.D.

Studies the applications and development of microarray technology.




Sanjay Tyagi, Ph.D.

Studies the behavior of nucleic acids in living cells. He is the co-inventor of molecular beacons.




David Wah, Ph.D.

Studies protein degradation and transcriptional complex assembly.




Shuishu Wang, Ph.D.

Studies drug target proteins encoded in the genome of Mycobacterium tuberculosis.