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  Symposium Announcement

"The Emergence of Carbapenem-Resistant Enterobacteriaceae"

 
The Public Health Research Institute, together with The New York Academy of Sciences, is organizing a symposium to discuss the molecular epidemiology of carbapenem-resistant Enterobacteriaceae, the complexity of their multidrug resistance, and the clinical challenges in both diagnosing resistance and treating immuncompromised patients.

The event will take place on Friday, February 17, 2012, at the New York Academy of Sciences. Presentations will be given by Robert Bonomo, MD, of Case Western Reserve University, Barry Kreiswirth, PhD, of the PHRI, and Thomas J. Walsh, MD of NY Presbyterian Hospital at Weill Cornell

For more details on this symposium and for registration, please visit the Academy's web site.



Paper Highlight - Vargas D.Y. et al, Cell 2011. Single-molecule imaging of transcriptionally coupled and uncoupled splicing

 
Introns are usually removed from pre-mRNAs during transcription while the pre-mRNA is still tethered to the gene locus via RNA polymerase. In a recent issue of Cell, PHRI investigator Sanjay Tyagi and his group describes circumstances under which splicing is uncoupled from transcription. They show that proteins that ensure that only a particular splice variant is expressed during alternative splicing, function by slowing the splicing to such an extent, that it is concluded post-transcriptionally after the release of pre-mRNA from the gene locus. This insight was gleaned using a unique single-molecule imaging approach that the group has developed earlier.

Their work appeared as a featured article in Cell (Vargas et al 2011, Cell 147, 1054 - 1065), which can be accessed at www.cell.com.

An interview conducted by Cell's editorial staff with Sanjay Tyagi about this work can be listened to at www.cell.com/../paperclip.mp3

In addition, the paper was highlighted in the December2011, Volume 5, No. 5 issue of the Inside NJMS publication of the New Jersey Medical School.



Dr. Xilin Zhao selected as a finalist in the University Science Center QED Proof-of-Concept Funding Program

  Dr. Xilin Zhao, PhD at the Public Health Research Institute Center of the University of Medicine and Dentistry of New Jersey has been selected as one of ten finalists to receive proof-of-concept funding for his work in developing a novel treatment for tuberculosis. As a finalist, Dr. Zhao has been matched with business advisers and received significant guidance on the development of a business plan and advice on marketing strategies and obtaining regulatory approval.

For additional information on the finalists selected, please click here



   
   

Employment Opportunities


  06.08.11   Senior Faculty Positions in Fundamental and Applied Infectious Diseases Research at the PHRI Center
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News & Noteworthy


  01.10.12   Last fall, Dr. Carmela Irene, a researcher at the Public Health Research Institute, participated as a volunteer for the New York Academy of Sciences, which collaborated with the Infosys USA Foundation, on an after school program for the Citizen Schools in New Jersey. An article on this successful program was posted on the Citizen Schools' web site ( www.citizenschools.org).
    
  10.01.11   In October 2011, the CNN Network broadcasted a one-hour documentary called "CNN Presents: Death by Mail - The Anthrax Letters." In this documentary, the new UMDNJ Regional Biocontainment Laboratory (RBL) was featured and interviews were conducted with Drs. David Perlin and Nancy Connell. Please follow this link to read more background information on the documentary at www.cnn.com.
    
  09.15.11   The NY Times published a letter submitted by PHRI Executive Director, Dr. David Perlin, entitled “‘Contagion’ Puts a Focus on Infectious Diseases”. Please follow this link to read the lettter at www.nytimes.com.
    
    
     Follow this link to view previous News & Noteworthy postings
    
    

Upcoming Seminar Series


  02.07.12   Lars Dietrich, New York University
Biological shape and pattern formation
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  02.14.12   Jean-Laurent Casanova, The Rockefeller University
Genetics of human disposition to pediatric infectious diseases
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