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"Tuberculosis: The Continuing Challenge"
- A Celebration to Honor the Career of Dr. Lee Reichman
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On December 14, 2009, the Public Health Research Institute Center at the UMDNJ – New Jersey Medical School hosted a symposium to celebrate the career of Dr. Lee Reichman.
The symposium took place at the PHRI Center / UMDNJ – New Jersey Medical School.
Presentations were provided by
Gerald Friedland of Yale University Medical Center,
Philip C. Hopewell of the University of California at San Francisco,
Michael D. Iseman of the University of Colorado,
Wafaa El-Sadr of the Harlem Hospital,
Melvin Spigelman of the Global Alliance against TB, and
Kenneth Castro of the CDC.
The speakers have graciously agreed to publish their presentations and you may download the series of presentations in a single PDF file (size is 10.5 MB) by selecting the following link: Download Symposium Presentations
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Paper Highlight |
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The first structure solved using data obtained from the PHRI X-ray Crystallography Core Facility was published in the Proceedings of the National Academy of Sciences.
The laboratory of Dr. David Wah solved the structure of the C-terminal domain of Transcription Factor IIB (TFIIB) from the infectious parasite Trypanosoma brucei,
the causative agent of African Sleeping sickness. T. brucei TFIIB is essential for the viability of this parasite. Strikingly, the putative DNA binding surface of T. brucei
is different from the DNA binding surface of human TFIIB, suggesting that T. brucei TFIIB binds DNA in a different way from human TFIIB. These results give insights into
transcriptional regulation in trypanosomes. A more thorough mechanistic understanding of the trypanosome transcriptional machinery will allow us to develop
new therapeutic tools against these parasites. The results are published in Proc Natl Acad Sci USA 2009, Volume 106, Number 32, pages 13242-13247.
To download a copy of this publication, please follow this link
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 Employment Opportunities
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News & Noteworthy |
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11.02.09 |
Karl Drlica, PHRI faculty and member of the Department of Microbiology and Molecular Genetics,
was selected the 2009 Graduate School of Biomedical Sciences at the NJ Medical School ‘Mentor of the Year.’
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10.14.09 |
On October 14th, 2009, the PHRI Center organizinged its 7th Annual Summer High School Intern Program Symposium.
Please download the Symposium Announcement
for more details.
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Upcoming Seminar Series |
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